Ans.216 *Filatov-Dukes disease*

*Filatov-Dukes disease* , also known as Staphylococcal scarlet fever, caused by Staph. aureus
epidermolytic toxin, described in 1900.
It is characterized by:
*. Sore throat
*. Fever
*. Bright red tongue with a"strawberry" appearance
*. Characteristic rash :
fine, red, and rough-textured; it blanches upon pressure.
*. appears 12–72 hours after the fever.
*. generally starts on the chest, armpits, and behind the ears.
*. spares the face (although some circumoral pallor is characteristic).
*. is worse in the skin folds . These Pastia lines (where the rash runs together in the armpits and groin) appear and can persist after the rash is gone.
*. may spread to cover the uvula .
*. The rash begins to fade three to four days after onset and desquamation (peeling) begins.