Four causes of anaemia in uraemic patients.
1. Erythropoietin deficiency
2. Increased levels of bone marrow toxins
3. Bone marrow fibrosis in osteitis fibrosa cystica
4.Increased red cell fragility by uraemic toxins
quizMED
ANAEMIA in URAEMIA
HER2/neu
HER2 is the target of the monoclonal antibody trastuzumab (marketed as Herceptin). Trastuzumab is effective only in cancers where HER2 is over-expressed.
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